HC016 cells modulate the inflammatory process by releasing specific enzymes and growth factors.
Cryopreserved H2O2-preconditioned human adipose-derived stem cells exhibit fast post-thaw recovery and enhanced bioactivity against oxidative stress - Journal of Tissue Engineering and Regenerative Medicine
"In vivo" Poc study finished with promising results.
"In vivo" Safety regulatory study finished with good safety profile.
Phase I/II clinical trial for Acute Respiratory Distress Syndrome (ARDS) was approved by the Spanish Agency of Medicines and Medical Devices in December 2019.
Phase I: Dose escalating Phase I study in 6 patients with moderate to severe ARDS inluded in 2 sequential cohorts. Phase finished in December 2020.
Phase II: Randomised, controlled, double-blind. 20 patients with moderate to severe ARDS divided into 2 groups (treated and control). Phase started in December 2021.